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By Oriol Güell

This thesis makes use of a systems-level method of research the mobile metabolism, unveiling new mechanisms and responses that have been most unlikely to arrive with conventional reductionists systems.

The effects mentioned the following have a possible software in parts like metabolic engineering and illness remedy. they can even be utilized in choosing the accuracy of the gene essentiality of recent genome-scale reconstructions.

Different tools and methods, in the contexts of structures Biology and the sector often called advanced Networks research were utilized during this paintings to teach various beneficial properties of the robustness of metabolic networks. the explicit concerns addressed right here variety from natural topological aspec

ts of the networks themselves to the stability of biochemical fluxes.

 

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A Network-Based Approach to Cell Metabolism: From Structure to Flux Balances (Springer Theses) by Oriol Güell


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